Chondroxide Gel Manufactured by Herbion Pakistan (Pvt.) Ltd in Patients with Osteoarthritis, Rheumatoid Arthritis, Cervical Spondylosis, and Frozen Shoulder
Saba Fatima,
Ifrah Hasan,
Muhammad Junaid
Issue:
Volume 9, Issue 4, July 2023
Pages:
60-64
Received:
5 September 2022
Accepted:
30 March 2023
Published:
11 July 2023
Abstract: Aims and Objective: Chondroxide gel is used topically in osteoarthritis, rheumatoid arthritis, cervical spondylosis, and frozen shoulder. This small-scale clinical survey was conducted to determine the safety and efficacy of the herbal product Chondroxide gel manufactured by Herbion Pakistan (Pvt.) Ltd. at Tulsi Medical Centre, Karachi, Pakistan. Introduction: Osteoarthritis is the most common disorder with joint pain and stiffness symptoms. Rheumatoid arthritis is a chronic inflammatory autoimmune disorder and another common reason for disability. At the same time, cervical spondylosis is a disease affecting the cervical spine, whereas a frozen shoulder often prolongs a disabling condition that can be managed by primary care. Method: This was a small-scale, open-labeled clinical survey. A total of 30 patients were enrolled in the study, out of which four patients got dropped out. 26 patients received Chondroxide gel. Statistical analysis was done by using the IBM SPSS 20. Results: Chondroxide gel was found safe and effective in treating osteoarthritis, rheumatoid arthritis, cervical spondylosis, and frozen shoulder and stated better response compared to the topical formulation available in the market. Conclusion: The results indicated improvement after applying the Chondroxide gel in patients with osteoarthritis, rheumatoid arthritis, cervical spondylosis, and frozen shoulder complaints and relieved external pain.
Abstract: Aims and Objective: Chondroxide gel is used topically in osteoarthritis, rheumatoid arthritis, cervical spondylosis, and frozen shoulder. This small-scale clinical survey was conducted to determine the safety and efficacy of the herbal product Chondroxide gel manufactured by Herbion Pakistan (Pvt.) Ltd. at Tulsi Medical Centre, Karachi, Pakistan. I...
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Colonization and Associated Risk Factors of Methicillin-Resistant Staphylococcus aureus Among People Living with HIV at Jimma Medical Center, Southwest Ethiopia
Mekonen Adisu,
Stephen Amankwah,
Rahel Tamrat,
Yared Alemu,
Tadele Akeba,
Mulualem Tadesse
Issue:
Volume 9, Issue 4, July 2023
Pages:
65-74
Received:
5 July 2023
Accepted:
20 July 2023
Published:
5 August 2023
Abstract: Nasal colonization of Methicillin-resistant Staphylococcus aureus (MRSA) is a potential source of spread and a prerequisite for staphylococcal infections. MRSA colonization, which causes infection in people living with HIV (PLWHIV), could lead to a longer hospital stay, increased medical costs, and prolonged antibiotic administration. This study aims to determine the nasal colonization rate, associated risk factors, and antibiotic susceptibility patterns of MRSA among PLWHIV at Jimma University Medical Center (JUMC), Southwest Ethiopia. An institution-based cross-sectional study was conducted among PLWHIV at JUMC from July to October 2021. Data on associated risk factors were collected by using a structured questionnaire and by reviewing patients’ medical records. Nasal swabs were cultured on mannitol salt agar and S. aureus was identified by the standard bacteriological procedures. S. aureus isolates were subjected to antibiotic susceptibility tests by the modified Kirby- Bauer disc diffusion method and resistance to the cefoxitin (30µg) disk signified MRSA. Binary and multivariable logistic regressions were employed to identify factors associated with MRSA nasal colonization, and a p-value < 0.05 was taken as statistically significant. A total of 351 PLWHIV were included in our study. The overall nasal colonization rate was 17.7% (62/351) for S. aureus and 6.0% (21/351) for MRSA. Hospitalization in the previous six months, 27.35 (95% CI: 4.042-185.08; p = 0.001), a viral load greater than 1000 copies/mL, 24.44 (95% CI: 1.885-317.12; p = 0.014) and rural residence, 9.49 (95% CI: 1.404-64.19; p = 0.021), were associated with increased odds of MRSA nasal colonization. Among the total MRSA isolates, 81.2% were multidrug resistant with the highest resistance rate against Erythromycin (85.8%), followed by Sulfamethoxazole-trimethoprim (66.6%), and Clindamycin (66.6%). Only 23.7% of MRSA isolates were resistant to Chloramphenicol and Gentamicin. A relatively low rate of MRSA nasal colonization was documented among PLWHIV. The majority of the MRSA isolates were, however, multidrug-resistant, which calls for regular screening of PLWHIV during their follow-up periods for the control and prevention of MRSA.
Abstract: Nasal colonization of Methicillin-resistant Staphylococcus aureus (MRSA) is a potential source of spread and a prerequisite for staphylococcal infections. MRSA colonization, which causes infection in people living with HIV (PLWHIV), could lead to a longer hospital stay, increased medical costs, and prolonged antibiotic administration. This study ai...
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