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Dyke-Davidoff-Masson Syndrome: A Case Report in a Filipino Male Adolescent
Lalaine Villaflor-Oida,
Rowena Cabradilla,
Michelle Sy,
Alejandro Bimbo Diaz,
Maria Antonia Aurora Valencia
Issue:
Volume 9, Issue 2, March 2023
Pages:
21-24
Received:
6 June 2022
Accepted:
6 July 2022
Published:
10 May 2023
Abstract: A previously well young Filipino boy presented with prolonged recurrent left focal to bilateral seizure. He was born of a non-consanguineous marriage, home-delivered vaginally, full term with no perinatal complications. He had normal growth and developmental milestones until at the age of 7 months when he developed febrile status epilepticus. Since then, he was left with residual left hemiplegia, dysarthria, cognitive delay and recurrent seizures occurring twice daily. He was poorly compliant on multiple anti-seizure medications. He was able to go to school and do activities of daily living with minimal supervision from his family. Symptoms of refractory seizures, hemiparesis, facial asymmetry, and intellectual disabilities along with brain imaging evidence of cerebral hemi-atrophy with compensatory calvarial thickening and subsequent hyperpneumatization is consistent with Dyke-Davidoff-Masson Syndrome (DDMS). A rare clinico-neuroradiologic condition occurring in fetal or early childhood period as a consequence of chronic brain insult. Diagnosis is established clinically with a characteristic cranial imaging finding. Hemi-spherectomy is the treatment of choice. This case will enlighten our mind as well as aid us in the prompt recognition of this uncommon syndrome with a classic clinico-radiologic presentation. Multidisciplinary intervention is essential, primarily to optimize seizure control as well as provide quality of life.
Abstract: A previously well young Filipino boy presented with prolonged recurrent left focal to bilateral seizure. He was born of a non-consanguineous marriage, home-delivered vaginally, full term with no perinatal complications. He had normal growth and developmental milestones until at the age of 7 months when he developed febrile status epilepticus. Since...
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Clinico-Biological Evaluation of Patients with Chronic Viral Hepatitis B on Tenofovir
Mayanna Habktéo,
Ali Mahamat Moussa,
Djerabet Franckly,
Eiba Tamam,
Tahir Mahamat Saleh,
Mairé Dehainssala
Issue:
Volume 9, Issue 2, March 2023
Pages:
25-28
Received:
20 March 2023
Accepted:
10 April 2023
Published:
10 May 2023
Abstract: Introduction: Viral hepatitis B is a major public health problem worldwide. The aim of this study was to evaluate the clinico-biological parameters in patients with chronic hepatitis B on Tenofovir. Patients and method: This was a cross-sectional study with retrospective data collection from April 1, 2019 to March 31, 2021, i.e. two years. Patients aged at least 15 years, regardless of sex, with a complete follow-up file were included. Results: A total of 920 files were evaluated, of which 145 met the inclusion criteria, i.e. a frequency of 15.76%. A male predominance was found (sex ratio 2.62). The average age was 33.24 years with extremes of 17 and 63 years. Students were more represented (36.6%). Incidental discovery was the most frequent mode (29.7%). Asthenia was the most frequent clinical manifestation (28.27%). Cytolysis was found in 82.76% of cases at the start of treatment. Creatinine levels were normal in most cases. HBV DNA was > 2000 IU/ml in 92.41% of cases. Abdominal ultrasound was normal in 51.25% of cases. Biological fibrosis scores (APRI and FIB-4) were used in almost one third of patients. The evolution was marked by a virological response of 82.35% at the 12th month and a normalization of transaminases in 91.6% of cases. Conclusion: Viral hepatitis B, a public health problem, is frequent among young people in our context. Tenofovir, effective, allows to obtain a significant virological response and a normalization of transaminases.
Abstract: Introduction: Viral hepatitis B is a major public health problem worldwide. The aim of this study was to evaluate the clinico-biological parameters in patients with chronic hepatitis B on Tenofovir. Patients and method: This was a cross-sectional study with retrospective data collection from April 1, 2019 to March 31, 2021, i.e. two years. Patients...
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Urine Leak After Partial Nephrectomy: A Rare Complication After Robot-Assisted Partial Nephrectomy
Kwabena Nkansah-Amankra,
Ameisha Tutwiler,
Zane Giffen,
Alberto Breda,
Wesley Ekeruo,
Firas Petros,
Obi Ekwenna
Issue:
Volume 9, Issue 2, March 2023
Pages:
29-41
Received:
13 April 2023
Accepted:
2 May 2023
Published:
10 May 2023
Abstract: In this systematic review, we looked at the rate of urine leakage from the kidney after surgical removal of kidney tumors. Urine leak (UL) is a common post-operative complication of partial nephrectomy (PN). The reported incidence varies in the literature, and there are no well-established guidelines for management of UL after PN. The goal of this study is to report the incidence and most common management strategies for UL after PN. For our quantitative synthesis, a systematic review of articles related to UL after PN from April 2010 to April 2020 was performed using PubMed and EMBASE. 475 total records were found, of which 40 reported on post-operative UL. A total of 19,904 cases were included. The overall incidence of UL was 2.8% (554/20,140). UL was most common in open cases (5.01%), followed by laparoscopic (4.40%) and robotic (1.18%) PN. Thirty-one of the included studies reported on management technique for a total of 343 interventions. UL was most frequently managed non-operatively (46.6%). Other management strategies included cystoscopy with ureteral stent placement (39.4%), percutaneous drain placement (8.7%), and percutaneous nephrostomy tube placement (2.3%). Use of nephrectomy, open reconstruction, angioembolization, or ureteroscopic techniques was uncommon (3.1%). Our study revealed that UL is rare after robotic approach to PN. Many reported cases have been managed conservatively. A stepwise management strategy is recommended. Most of these leaks heal with time or with placement of a stent into the ureter after surgery. We found that urine leak is less common with robotic surgery versus open or laparoscopic surgery.
Abstract: In this systematic review, we looked at the rate of urine leakage from the kidney after surgical removal of kidney tumors. Urine leak (UL) is a common post-operative complication of partial nephrectomy (PN). The reported incidence varies in the literature, and there are no well-established guidelines for management of UL after PN. The goal of this ...
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