Oral Albendazole Is Superior to Permethrin 5% for Scabies Treatment in Boarding School Indonesia
Fadhillah Ardiana Azmi,
Yeniar Fitrianingrum,
Ahmad Fiqri,
Siti Ma’rufah,
Moerbono Mochtar,
Suci Widhiati
Issue:
Volume 8, Issue 3, May 2022
Pages:
38-43
Received:
10 April 2022
Accepted:
25 April 2022
Published:
12 May 2022
Abstract: Scabies is a skin disease caused by Sarcoptes scabiei infestation and is classified as a neglected tropical disease (NTD). Permethrin 5% is the first-line treatment for scabies. However, adherence and accuracy in topical creams are common problems. Thus, it is necessary to think of alternative medication that is more accessible, more straightforward, and lower the risk of resistance. Albendazole appears to be an alternative therapy for eradicating scabies in the community base. Sixty subjects diagnosed with scabies were recruited and divided into two groups with randomization. The first group was given 400 mg oral albendazole for three consecutive days on the first and second week. The second group was applied permethrin 5% to the whole body once on the first night of the first and second week. The evaluation was carried out for four weeks, and improvement was stated absence of new lesions and healing of old lesions and pruritus. Data were analyzed using SPSS software (version 25, SPSS Inc., Chicago., IL). The X2 test was used to examine the difference between groups, and p < 0.05 was considered significant. The cure rate of albendazole was significantly superior to permethrin topical (90.0% vs. 63.3%) with a p-value of 0.015. This study revealed the effectiveness of oral albendazole 400 mg/day for three consecutive days in the first and second weeks for treating scabies to topical permethrin 5%. No side effect seen in the use of albendazole and topical permethrin during the study. Albendazole could be an alternative drug option to eradicate scabies in low-middle-income countries.
Abstract: Scabies is a skin disease caused by Sarcoptes scabiei infestation and is classified as a neglected tropical disease (NTD). Permethrin 5% is the first-line treatment for scabies. However, adherence and accuracy in topical creams are common problems. Thus, it is necessary to think of alternative medication that is more accessible, more straightforwar...
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The Mechanism Study of Head Rhythm Pattern Massage Consistent with Five-Tone Rhythm for Insomnia Patients
Issue:
Volume 8, Issue 3, May 2022
Pages:
44-49
Received:
6 June 2022
Accepted:
20 June 2022
Published:
30 June 2022
Abstract: Main research objectives: To observe and compare the effects of head rhythmic massage with five-tone rhythmic massage on the improvement of insomnia patients. Method: The sources of the cases are all from May 2020 to May 2021 in our hospital's Tuina ward, 60 patients with insomnia symptoms were selected. Randomly divided into two groups: Group A is treated with head rhythmic hand massage therapy consistent with the five-tone rhythm. The treatment group B is a traditional head massage method combined with five-line music therapy. Each treatment is 15 minutes, two times per day, five times per week, two weeks and one course of treatment, and one course of treatment. The Hamilton Anxiety Scale HAMA, the Bisborg Sleep Quality Index Scale PSQI and the Insomnia Severe Index Scale ISI were compared for all patients before and after treatment. The therapeutic effect of two groups was observed and the mechanism of action was discussed. Conclusion: Insomnia in both groups improved. But the head hand massage therapy which is consistent with the five-tone rhythm can relieve and improve the insomnia symptoms, and the curative effect is obviously better than the traditional massage therapy combined with the five-line music therapy in the treatment group B, which is worth clinical promotion.
Abstract: Main research objectives: To observe and compare the effects of head rhythmic massage with five-tone rhythmic massage on the improvement of insomnia patients. Method: The sources of the cases are all from May 2020 to May 2021 in our hospital's Tuina ward, 60 patients with insomnia symptoms were selected. Randomly divided into two groups: Group A is...
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