International Journal of Clinical and Experimental Medical Sciences

Volume 7, Issue 6, November 2021

  • The Term Ophthalmopathy of Prematurity More Fully Reflects the Problems in the Eye than Retinopathy of Prematurity

    Evgeny Ivanovich Sidorenko

    Issue: Volume 7, Issue 6, November 2021
    Pages: 160-164
    Received: Aug. 26, 2021
    Accepted: Sep. 17, 2021
    Published: Nov. 10, 2021
    DOI: 10.11648/j.ijcems.20210706.11
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    Abstract: Ophthalmopathy of prematurity (OH) was first described in 1942 by T. Terry and was named by him "Retrolental fibroplasia". Gradually, knowledge was accumulated that showed that retrolental fibroplasia is only the final stage of the process, and in 1951 Parker Heath proposed the term "Retinopathy of prematurity" (ROP). The development of science and... Show More
  • The First Preclinical Angiospastic Phase of Retinopathy (Оphthalmopathy) of Prematurity

    Evgeny Ivanovich Sidorenko

    Issue: Volume 7, Issue 6, November 2021
    Pages: 165-169
    Received: Sep. 02, 2021
    Accepted: Oct. 11, 2021
    Published: Nov. 10, 2021
    DOI: 10.11648/j.ijcems.20210706.12
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    Abstract: Retinopathy (ophthalmopathy) of premature infants (ROP) continues to be one of the complex and unresolved problems of pediatric ophthalmology, giving a high percentage of visual disability. ROP is a vasoproliferative disease and occurs in premature infants with a frequency of 16 to 40% of cases. Every year, about 15 million premature babies are bor... Show More
  • Assessment of Factors Associated with Low Measles Vaccine Effectiveness in Honkolo-Wabe District, Ethiopia

    Merga Gonfa Bati, Daba Mulleta, Wakgari Deresa, Bizuayehu Gurmesa

    Issue: Volume 7, Issue 6, November 2021
    Pages: 170-179
    Received: Oct. 05, 2021
    Accepted: Oct. 28, 2021
    Published: Nov. 12, 2021
    DOI: 10.11648/j.ijcems.20210706.13
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    Abstract: Background:-Measles is an acute illness and the most contagious childhood diseases. Almost all non-immune children contract this respiratory disease if exposed to the virus. The disease characterized by prodarmal fever, conjunctivitis, coryza and presence of Koplik spots. Prior to the introduction of vaccination programs, measles affected almost ev... Show More
  • Investigation of Changes in the Expression of Proinflammatory Cytokines Caused by Extract Silybum marianum L. in In-vitro and In-vivo

    Amir Akbarnejad Eshkalak, Hossein Maghsoudi

    Issue: Volume 7, Issue 6, November 2021
    Pages: 180-193
    Received: Oct. 09, 2021
    Accepted: Nov. 12, 2021
    Published: Nov. 23, 2021
    DOI: 10.11648/j.ijcems.20210706.14
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    Abstract: In this paper, the effects of alcoholic extract of Silybum marianum L. (AESM) on inflammation and reduction of cartilage destruction in a rabbit model with monosodium iodoacetate (MIA) osteoarthritis were investigated. AESM was able to effectively and dose-dependently suppress the mRNA expression of proinflammatory cytokines, including iL-6, iL-1α,... Show More
  • Procreation-Triggered Psychiatric Episodes, Maternal Mortality and Male Dominance in National Development: A Study of Selected Nigerian Gynotexts

    Iwabi Abraham Modahunsi, Emmanuel Babatunde Omobowale

    Issue: Volume 7, Issue 6, November 2021
    Pages: 194-199
    Received: Nov. 13, 2021
    Accepted: Nov. 30, 2021
    Published: Dec. 24, 2021
    DOI: 10.11648/j.ijcems.20210706.15
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    Abstract: The hazards related to parturition hardly feature in androtexts (male-authored texts). This is because men do not personally experience the pang of labor during childbirth. That some women procreate without hurdles does not make many people to realize that there are other women who have complications during pregnancy, labor and after parturition. P... Show More
  • Treatment Patterns and Outcomes in a Cohort of Finnish NSCLC Patients with ALK Rearrangement Reflect Rapid Evolution in Treatment Practices

    Heidi Loponen, Juuso Paajanen, Ville Vihervaara, Saija Ylä-Viteli, Klaus Tamminen, Saku Torvinen4, Jari Jokelainen, Tero Ylisaukko-oja, Maria Silvoniemi

    Issue: Volume 7, Issue 6, November 2021
    Pages: 200-209
    Received: Nov. 30, 2021
    Accepted: Dec. 15, 2021
    Published: Dec. 24, 2021
    DOI: 10.11648/j.ijcems.20210706.16
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    Abstract: Background: In Finland approximately 2,500 people are diagnosed with lung cancer annually. A small proportion of non-small cell lung cancer (NSCLC) patients (3–7%) have tumorigenic rearrangement of the anaplastic lymphoma kinase (ALK) gene (ALK-positive). ALK tyrosine kinase inhibitors (TKI) are the standard of care for these patients, showing supe... Show More