International Journal of Clinical and Experimental Medical Sciences

Volume 4, Issue 3, May 2018

  • Childhood Colostomy and Its Complications in Aba, Nigeria

    Ekpemo Samuel Chidi, Eleweke Ndubuisi, Chapp-Jumbo Assumpta

    Issue: Volume 4, Issue 3, May 2018
    Pages: 32-34
    Received: 17 March 2018
    Accepted: 17 May 2018
    Published: 19 June 2018
    Abstract: Background: Colostomy in paediatric surgical practise is still important for decompression in colonic bowel obstruction, trauma to the colon and perineum in children. Objective: To determine the indications and complications arising from childhood colostomy in Aba, Nigeria. Methods: Proforma was opened for consecutive children that had colostomy at... Show More
  • Analgesic Effect of Viddha, A Nonpharmacological, CostEffective Local Therapy of Ayurveda (An Indian System of Medicine) in Knee Osteoarthritis (OA): A Case Report

    Vishakha Rajesh Wetal, Arun Gupta

    Issue: Volume 4, Issue 3, May 2018
    Pages: 35-38
    Received: 28 April 2018
    Accepted: 31 May 2018
    Published: 28 June 2018
    Abstract: Objective: Global statistics reveal over 100 million people worldwide suffer from OA, which is one of the most common causes of disability. According to the Arthritis Foundation, one in every two will develop symptoms of knee OA during their lives. One of the primary symptoms of persons with knee osteoarthritis is pain. The objective of this case r... Show More
  • Analysis of Status and Risk Factors for Macrovascular Complications in Type 2 Diabetes Mellitus

    Rui Han, Wei Yang, Dan Yang, Xia Dong, Lin Song, Hua Liu

    Issue: Volume 4, Issue 3, May 2018
    Pages: 39-45
    Received: 9 June 2018
    Accepted: 26 June 2018
    Published: 24 August 2018
    Abstract: The status and risk factors for atherosclerosis (AS) were investigated and the sensitivity and accuracy of existing examine methods of AS were evaluated in patients with diabetes mellitus(T2DM). Ninety nine patients who diagnosed with the WHO 1999 criteria for T2DM were enrolled in this study, which were divided into atherosclerotic group(group A) ... Show More
  • The Role of Gap Junction in Regulating Vascular Function and Its Relationship with Hypertension

    Jian Hu, Shiying Liu, Yuanzhi Qiu

    Issue: Volume 4, Issue 3, May 2018
    Pages: 46-50
    Received: 11 June 2018
    Accepted: 30 July 2018
    Published: 27 August 2018
    Abstract: Gap junction (GJ), also called as gap connection, communication connection, is a special membrane structure which consisted of connecting channels in two adjacent cells. Intercellular communication can be divided into indirect and direct communication. Direct communication is a cell-to-cell communication mediated by GJ between adjacent cells. Direc... Show More
  • Cannabidiol Attenuates Palmitic Acid-Induced Injury in Cultured Hepatocytes Through Promoting Autophagic Flux

    Rui Chen, Xiaogang Gao, Lei Zhang, Wenyu Zhao, Li Zeng, Youhua Zhu, Zhiren Fu

    Issue: Volume 4, Issue 3, May 2018
    Pages: 51-56
    Received: 21 June 2018
    Accepted: 2 August 2018
    Published: 31 August 2018
    Abstract: Objective: This work was designed to investigate the protection of cannabidiol (CBD) against palmitic acid (PA)-induced injury in cultured hepatocytes and the underlying mechanism associated with autophagic flux. Methods: Experiment 1: Primary cultured hepatocytes were stimulated with PA (800 μmol/L) and treated with CBD (5 μmol/L) and chloroquine ... Show More