Fixed Time and Fixed Angle External Fixation in the Treatment of Gartland Type III Supracondylar Humerous Fractures in Children
Wei Cai,
Yang Wenbin,
Liao Hailang,
Zeng Lingyuan
Issue:
Volume 4, Issue 4, July 2018
Pages:
57-62
Received:
15 August 2018
Accepted:
14 September 2018
Published:
12 October 2018
Abstract: Objective: To assess the efficacy of open reduction internal fixation (ORIF) combined with fixed-time and fixed-angle external fixation (FTFAEF) in the treatment of Gartland type III supracondylar humerous fracture (SHF) in children. Methods: Clinical data of 172 children with Gartland type III SHF from March 2012 to December 2017 were prospectively analyzed. All 172 patients were initially treated with ORIF, then 86 underwent FTFAEF for 3 weeks post-surgery (intervention group) while the remaining 86 received conventional plaster external fixation (70°-90°) for 3 weeks post-surgery (control group). The plaster casts were removed from both groups after the 3-week fixation period and functional exercise was initiated. Regular clinical and radiologic follow-ups were conducted on all patients. Range of motion (ROM) measurements and modified Hospital for Special Surgery (HSS) elbow function assessments were performed at 1 and 3 months post-surgery. Results: At 1 month post-surgery, both ROM and modified HSS scores were significantly higher in the intervention group (85.8±6.1° and 65.2±3.6°, respectively) than in the control group (62.3±5.2° and 56.6±2.1°, respectively)(both P<0.05). After 3 months, both ROM and modified HSS scores were still significantly higher in the intervention group (132.0±4.7° and 98.5±1.3°, respectively) than in the control group (107.5±24.4° and 85.0±10.3°, respectively) (both P<0.05). Furthermore, the percentage of patients scoring excellent on the HSS scale was significantly higher in the intervention group (100%) than in the control group (74.42%) (P<0.05). Conclusions: ORIF combined with FTFAEF is an efficacious approach that should be widely promoted for the treatment of Gartland type III SHF in children.
Abstract: Objective: To assess the efficacy of open reduction internal fixation (ORIF) combined with fixed-time and fixed-angle external fixation (FTFAEF) in the treatment of Gartland type III supracondylar humerous fracture (SHF) in children. Methods: Clinical data of 172 children with Gartland type III SHF from March 2012 to December 2017 were prospectivel...
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A Mouse Model for Inflammatory Bowel Disease Associated Tumorigenesis
Zexian Chen,
Yongle Chen,
Xiaowen He,
Ping Lan
Issue:
Volume 4, Issue 4, July 2018
Pages:
63-67
Received:
6 September 2018
Accepted:
20 September 2018
Published:
12 October 2018
Abstract: Inflammatory bowel disease, including Crohn’s disease and ulcerative colitis, is one kind of chronic, relapsing inflammatory disorder of the gastrointestinal tract and has the potential of tumorigenesis. However, no stable and mature cell line is available for relative basic research, so animal model is essential. In this study, a mice model was built, which mimics the dynamic disease course of inflammatory bowel disease associated tumorigenesis with injection of azoxymethane and sequent cycles of drinking water with dextran sulfate sodium. All the mice survived till the end of the modeling procedure. Compared with the mice in the control group, the mice in the modeling group experienced obvious bloody diarrhea and body weight loss (P<0.001). The colorectum was significantly swollen and shorter (P<0.001) while the spleen was significantly bigger (P<0.001) in mice in the modeling group compared with the mice in the control group. All the mice in the modeling group developed tumors in the colorectum, with an average tumor number of 6.5 and an average tumor size of 10.25 mm3. Pathological evaluation by hematoxylin and eosin staining confirmed the tumors as adenomas with high-grade dysplasia. In conclusion, this model is inducible and stable which would be very useful in the research in this field.
Abstract: Inflammatory bowel disease, including Crohn’s disease and ulcerative colitis, is one kind of chronic, relapsing inflammatory disorder of the gastrointestinal tract and has the potential of tumorigenesis. However, no stable and mature cell line is available for relative basic research, so animal model is essential. In this study, a mice model was bu...
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Military and Medical Expertise in Patients with Central Retinal Degeneration
Ignatiev Sergei,
Alekseev Igor,
Nam Yuliya
Issue:
Volume 4, Issue 4, July 2018
Pages:
68-72
Received:
17 September 2018
Accepted:
24 October 2018
Published:
14 November 2018
Abstract: Last years pathological processes of the retina became a worldwide problem among people of different ages and this group includes a various number of central retinal degenerations. There is a vivid tendency for these types of diseases to become younger last years. Such changes are the most common reasons of vision loss, especially age-related macular degeneration and its exudative form. Recent studies show that this form of AMD is linked not only with aging, weakness of the vessels and free radical oxidation, but also with non-specific immune stimulation and the potential role as a trigger of cytomegalovirus infection. No wonder, that chronic infection of endothelial cells leads to attracting to inflammation region of macrophages, their adhesion and synthesis of anti-inflammation cytokines and after all if stimulates formation or activation of CNV. Some pathogenetic peculiarities, methods of treatment and medical expertise are described in this article. Still, they are in the first rate in studies of ophthalmologists all over the world. Social meaning of this pathology is important due to the developing of disability in population and especially in military personnel. The article provides chronic, difficult curable or incurable diseases and outcomes of injuries and burns of the eyes. The matter is that in cases with a completed process or a progressing course with rare exacerbations (less than 2 times per year), the category of fitness for military service is determined depending on the eye functions strictly in accordance with the relevant articles of the disease schedule.
Abstract: Last years pathological processes of the retina became a worldwide problem among people of different ages and this group includes a various number of central retinal degenerations. There is a vivid tendency for these types of diseases to become younger last years. Such changes are the most common reasons of vision loss, especially age-related macul...
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