Review Article
Analysis on Syndrome and Treatment of Shaoyin Cold Type Acute Tonsillitis
Yan Yang tian
,
Yan Ying*
Issue:
Volume 10, Issue 4, August 2024
Pages:
43-47
Received:
28 August 2024
Accepted:
18 September 2024
Published:
29 September 2024
Abstract: Acute tonsillitis belongs to the category of "milk moth" in traditional Chinese medicine. TCM clinical syndrome differentiation is often divided into two types: wind-heat pathogens affecting the lung meridian and dietary excess leading to heat accumulation in the lungs and stomach. The author's clinical practice found that some acute tonsillitis patients are often manifested as Shaoyin cold type, and the syndrome and treatment of general acute tonsillitis are totally different. "Throat Science Family Instructions" put forward the specific treatment of pharyngeal pain is Shaoyin typhoid type, and the prescription is Banxia Gangui Decoction, which is composed of eight kinds of drugs: Guizhi, Banxia, Fuling, Jiegeng, Yiyiren, Buguzhi, Ganjiang, and Zexie. It is traditionally used to treat symptoms such as sore throat, diarrhea, deep and thin pulse, and white tongue coating without thirst. Combining theory and clinical experience, the author reports successful clinical outcomes using this decoction to treat acute tonsillitis of the Shaoyin cold type. This paper aims to analyze the internal connection between Banxia Gangui Decoction and Shaoyin cold type acute tonsillitis. The paper outlines the symptom characteristics, etiology and pathogenesis, treatment based on syndrome differentiation, differential diagnosis of this condition, along with the therapeutic rationale for Banxia Gangui Decoction. A case study is included.
Abstract: Acute tonsillitis belongs to the category of "milk moth" in traditional Chinese medicine. TCM clinical syndrome differentiation is often divided into two types: wind-heat pathogens affecting the lung meridian and dietary excess leading to heat accumulation in the lungs and stomach. The author's clinical practice found that some acute tonsillitis pa...
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Research Article
Histopathological Characterization and Development of Objective Diagnostic Criteria in Mycosis Fungoides
Ignacio Pinilla-Pagnon*,
Rosa Rojo-López,
Tania Sierra Hompanera,
Gonzalo Garcia de Casasola,
Montserrat Chao-Crecente
Issue:
Volume 10, Issue 4, August 2024
Pages:
48-59
Received:
12 September 2024
Accepted:
18 October 2024
Published:
13 November 2024
Abstract: Background: Mycosis Fungoides is a subtype of Cutaneous T Cell Lymphomas, often difficult to diagnose in its early stages due to its histopathological resemblance to inflammatory dermatoses. Objectives: To refine and enhance the diagnostic criteria for Mycosis Fungoides by utilizing digital scanning and analysis systems for the quantitative evaluation of immunohistochemical markers. Methods: A retrospective longitudinal observational descriptive study based on the reevaluation and comparison of diagnostic criteria (histological and immunohistochemical) of patients with a clinical suspicion of MF, creating two groups: patients whose diagnosis, despite requiring numerous biopsies, was finally Mycosis Fungoides (MF Group), and patients who, despite clinical suspicion, always had a diagnosis of Inflammatory Dermatoses (Control Group). The study was conducted on 62 patients with clinical suspicion of MF who underwent punch biopsies between 2000 and 2022 at Severo Ochoa University Hospital. Histological and immunohistochemical markers (CD2, CD3, CD4, CD5, CD7, CD8, TOX) were assessed using APERIO AT2 LEICA BIOSYSTEMS scanner and CIVAGENIUS software, ensuring objective and reproducible results. Results: Basal epidermotropism, lymphocytic atypia, and peri-lymphocytic halo showed strong associations with MF diagnosis. Significant differences were observed in the CD3/CD8 and CD5/CD8 ratios between Mycosis Fungoides and Inflammatory Dermatoses groups. High TOX antibody expression correlated with early-stage MF diagnosis. These findings suggest the potential of combining marker ratios and TOX expression with digital analysis to improve diagnostic accuracy. Conclusions: Digital scanning and automated analysis systems significantly enhance the precision and efficiency of Mycosis Fungoides diagnosis. Implementing these methods in routine practice can reduce diagnostic delays and improve patient outcomes by differentiating Mycosis Fungoides from similar dermatological conditions more effectively.
Abstract: Background: Mycosis Fungoides is a subtype of Cutaneous T Cell Lymphomas, often difficult to diagnose in its early stages due to its histopathological resemblance to inflammatory dermatoses. Objectives: To refine and enhance the diagnostic criteria for Mycosis Fungoides by utilizing digital scanning and analysis systems for the quantitative evaluat...
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