International Journal of Clinical and Experimental Medical Sciences

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Research Article |

Analysis of a Case of Colon Cancer Complicated with Diffuse Large B-Cell Lymphoma of the Spleen

Background: Primary splenic lymphoma (PSL) is a rare type of tumor that occurs in the spleen, generally without the involvement of intrasplenic organs and lymph nodes, and its incidence is less than 1% of lymphomas, most of which are non-Hodgkin's lymphomas (NHL). Diffuse large B-cell lymphoma (DL- BCL) often has atypical clinical manifestations, which makes clinical diagnosis difficult and is prone to misdiagnosis or omission, posing a significant challenge to clinical diagnosis and treatment. Colorectal cancer is the third most frequent cancer and the fourth most common cause of death in the world and is diagnosed on the basis of clinical manifestations, X-ray barium enema, or fibreoptic colonoscopy. The key to colorectal cancer treatment lies in early detection, timely diagnosis, and surgical eradication. Although lymphoma and colorectal cancer are some of the most frequent malignant tumours in adults, and there are guidelines for the diagnosis and treatment of both diseases, their co-occurrence is extremely uncommon, and there are fewer reports in the literature on the diagnosis and treatment of co-existing cases, and there is still no definitive and effective method for diagnosis, differential diagnosis and treatment. A case of splenic diffuse large B-cell lymphoma complicated with colon cancer was admitted to our hospital, and we now report its clinical data, conduct a literature review and analysis in order better to carry out clinical diagnosis, differential diagnosis and treatment, and summarize the diagnosis and comprehensive treatment experience of this disease. This case report provides ideas for the diagnosis and treatment of the disease.

Primary Splenic Lymphoma, Diffuse Large B-Cell Lymphoma, Colon Cancer

Guoqing Huang, Chulin Liang, Mingzhi Sang, Xuyou Liu. (2023). Analysis of a Case of Colon Cancer Complicated with Diffuse Large B-Cell Lymphoma of the Spleen. International Journal of Clinical and Experimental Medical Sciences, 9(5), 79-84.

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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